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The expression of GCL is highly sensitive to environmental threats and is upregulated by the Nrf2 transcription factor when the cell detects oxidative stress

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This process can enhance nutrient and oxygen delivery to areas requiring healing

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Finally, preliminary cellular research using glutathione monoesters has been shown to be an effective delivery agent of glutathione due to improved bioavailability [47]

It creates a protective microenvironment around the peptide, temporarily buffering the local pH and enhancing membrane permeability