A healthy gut environment allows for better nutrient uptake, including antioxidants
BPC-157, a peptide derived from human gastric juice, has shown promise in accelerating healing and reducing inflammation in preclinical models
Therefore, it is possible that the increased mTORC1 activation measured in FoB upon Gclc deletion can be a consequence of ROS accumulation and activation of the PI3K/AKT axis
Medication interactions matter too, especially with drugs like insulin or blood thinners
For example, insulin is an essential hormone that controls energy storage
in Nature Medicine found that NNMT inhibition in white adipose tissue increased energy expenditure and reduced fat mass in animal models without altering food intake or physical activity (Kraus et al., Nature Medicine )