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ADCs with branched PEG chains (e.g., PEG24) demonstrate lower hydrophobicity, extended circulation time, and superior anti-tumor activity compared to non-PEGylated variants (Figure 15)

It has been shown to have the capacity to affect several vital functions of the body

The regulatory role of the N-terminal region of CGS has also been described upon induction of folate deficiency in Arabidopsis (Loizeau et al., 2007)

Combination therapy of Ad-mda7 and Herceptin inhibits tumor growth in nude mice and increases apoptosis in Her2/neu overexpressing breast cancer cells

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

b Cyto, Cytosolic