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IGFBP-2 partly mediates the early metabolic improvements caused by bariatric surgery

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Low oral bioavailability results in substantially higher API volume requirements, increasing raw material consumption and production intensity

Registration and Protocol Our systematic review and meta-analysis protocol has been registered and published in PROSPERO (Registration number: CRD42021232433)

The effect was more pronounced with myo-inositol and in participants with overweight or obesity