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Eur Rev Med Pharmacol Sci (2017) 21(2 Suppl):519

As demonstrated for MOR, the phosphorylation-deficient DOR mutant (T358A/T361A/S363G) is able to undergo internalization upon DPDPE activation but to a lesser extent than the wild type (Zhang et al., 2005)

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After 24 h, the mice were euthanized and evaluated for peptide adsorption and penetration analysis by histological examination

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Storing lyophilized PT-141 at -20C (-4F) or colder will keep it stable for years