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It is not appropriate for pregnant individuals and should be avoided in patients with personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2

So what happened here

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It's the first 'to directly compare the efficacy and safety of two oral GLP-1 receptor agonists in a randomised controlled trial', reports Medscape. The part about 'directly comparing' the two drugs is important

Semaglutide, injected once a week, has stronger hypoglycemic and weight loss effects, and has a lower risk of hypoglycemia

[11] Brand-Miller et al., (2002) Glycemic index and obesity, The American Journal of Clinical Nutrition, Volume 76, Issue 1, Pages 281S-285S, ISSN 0002-9165, ajcn/76.1.281S