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Per a 2021 analysis published in Diabetes Obesity Metabolism , nearly 50% of patients on semaglutide report nausea.41 Side effects tend to be dose dependent and may lessen in intensity with ongoing treatment.42,43 An underlying cause for these GI complaints relates to one of the ways in which GLP-1 medications work, which involves delayed gastric emptying

GIP and glucagon co-stimulation may alter gallbladder function, but this effect is less studied

Deponte, M., Becker, K

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Based on target consumer, GLP-1 Users for Weight Management represent approximately 31.80% share in 2026, driven by the high adoption of GLP-1 agonists specifically for weight loss and the corresponding need for protein, hydration, and micronutrient support