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In vitro patch-clamp electrophysiological recordings revealed that modulating the electrophysiological properties of both POMC and cocaine- and amphetamine-regulated transcript (CART) neurons (POMC/CART neurons) and NPY/AgRP neurons are the possible mechanism of liraglutide-induced weight loss (Secher et al., 2014)

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In the original cross-over trial clinical improvement was accompanied by migration of datapoints towards the control zone in the nomogram relating serum levels of a lipid oxidation marker and selenium (Figure 3) (160)

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