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Topical drug delivery relies on passive diffusion, and prolonged drug retention helps improve efficacy

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In addition to lactobacilli , other bacterial species including Pseudomonas and Burkholderia , as well as bacterial metabolites such as butyrate, inhibit Candida yeast to hypha transition

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These are risky for sports performance and often banned

Nevertheless, studies had relatively small samples, and there arent any long-term data available yet