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For the NAC rescue experiment, mice received intraperitoneal administration of 200 mg/kg of body weight NAC (A105422, Aladdin) in phosphate-buffered saline (pH 7.4) every second day for two weeks

In addition to this major function, the walls of the intestinal tract also act as a protective barrier for the bloodstream and the organs

It is used in pharmaceutical and food application as dietary supplement, and found as well an application in cosmetics

These reductions represented estimated treatment differences ranging from 3.0% to 7.8% weight loss versus placebo, all of which were statistically significant