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Two ubiquitination pathways regulate lysophagy, and they involve galectins (Gals) and SCF FBXO27 26,83,84,85

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Following T cell activation, the B7-1B7-2 interaction with CTLA-4, expressed on activated T cells, leads to down-regulation of T cell activation, whereas stimulation of the TCR alone leads to T cell clonal anergy

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