RCTs should be adequately powered with defined orthopaedic indications
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Besides disruption of liver histoarchitecture (including vascular dilation and congestion), hepatocyte degeneration, increased serum AST and alanine aminotransferase (ALT) levels, enhanced oxidative stress, and pronounced infiltration of inflammatory cells accompanied by upregulation of pro-inflammatory genes were observed [151]
10.1034/j.1399-3003.2000.16b12.x
Broadfield LA, Saigal A, Szamosi JC, et al