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Lipid ROS, a classic biomarker of ferroptosis, was accumulated in VRK2-KO cells following APR-017 treatment (Fig

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Following primary tumor removal, mice were continuously measured for lung metastases using bioluminescence imaging once a week until reaching end point, or poor body condition in accordance with animal welfare guidelines

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At the 1st and 2nd hours, all groups showed measurable increases in paw volume

Thick collagen bundles arranged parallel to the skin surface