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I wonder how much of the homology is explained by receptor homology, and how much by pharmacological/trafficking needs--i.e

10.1111/dom.12736 71

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Cons Requires consistent daily use for optimal results

Insulin directly lowers blood sugar by promoting glucose uptake into cells

BB mainly contributed to sections Introduction, BloodBrain Barrier, BloodCerebrospinal Fluid Barrier, and Neurovascular Unit, and Selenium Transport to The Brain Selenoprotein P and Low Molecular Weight Selenium-Species. BM mainly contributed to sections Introduction, Selenium Transport to The Brain Selenoprotein P and Low Molecular Weight Selenium-Species, and Conclusion and Perspectives. All authors contributed to the editing and discussion and agreed to submit the manuscript in its current state