The best alternative depends on the reason for treatment
114 The density of AMPA, NMDA and P2X receptors as well as the density of plasmalemmal glutamate transporter currents demonstrates bell-shaped age dependency, with maximal densities observed in adult animals, whereas ageing is accompanied by a 2-3 fold decrease of density of respective ion currents
Diabetes 67 (Suppl
In addition, high levels of it can end up accumulating inside the brain causing irreversible damage in areas such as the basal ganglia, producing kernicterus or bilirubin encephalopathy (1, 2)
It targets GLP-1, GIP, and glucagon receptors simultaneously, adding a third mechanism that directly increases energy expenditure and fat oxidation through the liver
Hypoglycemia can occur in individuals with type 2 diabetes, especially when they are taking insulin or insulin secretagogues like sulfonylureas [39,40]