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The main ROS involved in redox signaling is hydrogen peroxide

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SIRT3 enhances the enzymatic activities of SOD2 and IDH2 to limit ROS levels, which repress the metabolism reprogramming in cancer cell via destabilizing HIF-1, thereby repressing tumor growth

[1] It is administered as a once-weekly subcutaneous injection starting at 2.5 mg with gradual 4-week titration increments

Because BB10 peptide is a research-use compound, there is no universal dosage recommendation for personal use

"I was surprised because I'd tried so many other ways and the scale did not budge