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Deficiency in B12 can result in symptoms such as trouble concentrating, memory problems, and mood changes

Research by Cerovecki et al

In lab and clinical research, its been observed to activate fibroblasts (the cells that produce collagen), increase glycosaminoglycan synthesis (which helps skin retain water), modulate matrix metalloproteinases (MMPs, the enzymes that break down old tissue), and act as a copper cofactor in antioxidant pathways

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Researchers generally describe these effects as dose- and duration-dependent rather than inherent to any exposure level