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A human homolog of angiotensin-converting enzyme

To enhance biological interpretability, we examined the ratio of aKG to creatine

1-3 Glutathione is also involved in the metabolism of certain compounds that can increase free radical activity

Therefore, the regulation of ROS homeostasis is crucial for maintaining the health of humans

Toxicology 149:4350 Thomas C, Mackey MM, Diaz AA, Cox DP (2009) Hydroxyl radical is produced via the Fenton reaction in submitochondrial particles under oxidative stress: implications for diseases associated with iron accumulation

465 Both iron overload or deficiency can precipitate heart failure by disrupting iron homeostasis within cardiomyocytes