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Andersen, F

[5] While the precise mechanisms of action for NAD+ therapys purported benefits are not fully elucidated, multiple lines of research suggest several contributing effects

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[18] [19] According to a 1961 study, patients with addiction who got NAD+ at a moderate IV drip rate (no more than 35 drops per minute) reported no distress but those who received it at a quicker drip rate complained of headache and shortness of breath