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and decreased mitochondrial aconitase activity and mitochondrial membrane potential are observed in HepG2 lines overexpressing CYP2E1 in mitochondria (mE10 and mE27 cells) treated with BSO as compared with cells transfected with empty vector (pCI-neo) [5]

However, if your skin appears dull or has uneven pigmentation, brightness may be your first priority

Age Group Hyperpigmentation can affect individuals of any age group, but it becomes more common with advancing age due to cumulative sun exposure and hormonal changes

[DOI] [PubMed] [Google Scholar] 33.Lemasters JJ

This growing public health challenge highlights the limitations of existing therapies and the pressing demand for disease-modifying treatments that go beyond symptomatic relief (Wang et al., 2024)

& Goa, K