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R 3 are R 5 are each independently H, or C 1 -C 6 alkyl

Based on the available data, these drugs are great as adjunct OSA treatments, which include CPAP therapy for most patients. Tirzepatide significantly improved OSA outcomes, with concomitant reduction in body weight, compared with placebo in the SURMOUNT-OSA study

Pocai A, Carrington PE, Adams JR, et al

[1] [2] Semaglutide mimics the action of the naturally occurring hormone GLP-1, which is released from the intestine after eating

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