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A rare lethal fatty acid oxidation defect

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The MGBA refers to the bidirectional communication network linking the guts resident microbiota and the central nervous system (CNS) [8,9,10]

Moreover, IRE1 is a central regulator of B-cell differentiation, and both B-lymphocyte maturation and antibody plasma cell differentiation are regulated by the IRE1-XBP1 axis (75, 76)

NOX2 and nitric oxide synthase use NADPH as a cofactor to produce free radicals [120]

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