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We previously reported significantly increased ROS levels in the sera and livers of HCV-infected tree shrew, which is an emerging small animal model of the Tupaiidae family susceptible to HCV infection 56,57

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Gln inhibits miR-29b-3p transcription via c-Myc regulation to promote GGCT protein expression To determine GGCT downregulation during Gln deprivation, we first excluded protein degradation pathways as proteasomes (MG132) or lysosomes (CQ) inhibition failed to restore GGCT levels (Fig

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