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Meldonium, the modulator of inflammation-induced MD Hypoxia induced at high altitudes or during intense physical exertion causes a series of modifications such as polycythemia, increased levels of proinflammatory cytokines (IL1, IL6, and TNF) in lung tissue, and changes in parameters of oxidative stress (elevated lipid peroxidation product and protein carbonyl content as well as decreased GSH and total antioxidant capacity), all of which lead to MD [29]
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Anti-nausea strategies including ginger, acupressure, or prescribed antiemetics may benefit patients with prominent nausea
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