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Key markers include fasting glucose and insulin (to assess insulin sensitivity), HbA1c (long-term glucose regulation), lipid panel (triglycerides, HDL, LDL), resting metabolic rate via indirect calorimetry, and body composition via DEXA scan (to differentiate fat loss from lean mass changes)

Hierarchy of Evidence: Level A (Human meta-analyses and systematic reviews of CNS drug delivery)

We have to get it from food or supplements

Brain Res Bull 174:4152

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In a group of patients ( n = 127) with iron-deficiency anaemia, 79.5% reported headaches and 36.2% met the criteria for migraine