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Real-world observational data from pharmacy and health system databases support these trial findings, showing low hypoglycemia incidence when semaglutide is prescribed without concurrent insulin or sulfonylureas

TIL, when starving, switch to fatty acid metabolism as was shown by decreases in glycolysis metabolites accompanied by increases in TCA cycle metabolites (62)

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Early generic entrants may price products at higher margins initially, with costs declining as additional manufacturers receive Health Canada approval and enter the Canadian market

Finally, the patent protection they hold allows them to set the market price without immediate competition