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Running alongside these is TRIUMPH-CVOT, a separate cardiovascular outcomes trial enrolling around 10,000 participants with established cardiovascular disease over 3-4 years

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The two peptides reach overlapping outcomes both are pro-angiogenic and both improve functional scores in some injury models but the routes are largely different

Liver Fat: Sanyal et al., 2024 (Nature Medicine) Sanyal, Kaplan, Fras, Brouwers, and colleagues reported a phase 2a, randomized, placebo-controlled trial in adults with metabolic dysfunction-associated steatotic liver disease (MASLD) in Nature Medicine in 2024 [6]

The differential DNA methylation of certain maternal and paternal alleles in the 15q11.2q13 region provides a tool for assessing paternal-only, maternal-only and normal (biparental) inheritance