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Its too early to know if too much B12, based on high levels from a blood test, is a health concern

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[20] Treatment of megaloblastic anemia with concurrent vitamin B 12 deficiency using B 12 vitamers (including cyanocobalamin), creates the possibility of hypokalemia due to increased erythropoiesis (red blood cell production) and consequent cellular uptake of potassium upon anemia resolution

The study showed that the administration of 10.000 ugr of hydroxocobalamin nasal drops twice weekly was associated with a significant increase in vitamin B12 serum levels over the course of 3 months, starting from a median of 328 pmol/l (range 244429) to 973 pmol/l (range 4731,476)

[4] Niacinamide (vitamin B) forms the coenzymes NAD and NADP, which are involved in hundreds of oxidation-reduction reactions in cells

M.ShamshuddinZ.BhatK.SivadasA.MandalA