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The experiment involved several treatment groups across multiple animal models

It does not constitute medical advice, diagnosis, or treatment recommendations

Future studies should use lower doses to determine the threshold concentration of B12 in the gut necessary to change the activities of the microbiota, particularly in the Lachnospiraceae populations and how these changes impact microbe-host interactions in the gut with a specific focus on IL-12p40 cytokine production along the GI tract

Common side effects associated with B12 supplementation include: Local injection site reactions (for intramuscular preparations): Pain, redness, or swelling at the injection site Mild bruising or tenderness Itching localised to the injection area These reactions are usually self-limiting and resolve within 2448 hours

includes warnings that parenteral thiamine may cause anaphylaxis and that the benzyl alcohol preservative is contraindicated in neonates due to risk of serious reactions)

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