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An observational study published in the BMJ in 2016 found no increased risk of breast cancer among GLP-1 analog users when compared to DPP-4 inhibitor users (HR 1.40 (95%CI [0.91 to 2.16])

Users report eating smaller and more frequent meals, as well as an overall reduction in what is generally considered bad for you foods like fast food and items high in sugar/fat (see Figure 2 )

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The interaction between Tirzepatide and creatine is not a direct drug-drug collision, but rather an indirect effect on your baseline kidney function and workload