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Key studies include: Weight regain and cardiometabolic effects after withdrawal of semaglutide (STEP-1 trial extension): This study found that participants regained about two-thirds of the weight they had lost within one year after stopping semaglutide

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Many patients report feeling satisfied with smaller portion sizes and experiencing reduced interest in food between meals

Potential impact on food preferences: Some studies and patient reports suggest that GLP-1 medications like Rybelsus may decrease cravings for high-fat, sugary, or processed foods

Medication Administration: Semaglutide is usually administered through weekly injections or daily oral medication, depending on the chosen formulation