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For best results and safety, its important to follow the storage instructions that come with your medication

The same review also notes that topical products commonly use alpha arbutin at 0.1% to 2% , with a recommended pH between 4.0 and 6.0 for stability and effectiveness

Toxicol Pathol (1989) 17(2):26693

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Foods rich in monounsaturated and polyunsaturated fats, such as avocados, nuts, seeds, and oils like olive and flaxseed, should be included

Suffers of the serious genetic condition phenylketonuria (PKU) are unable to convert phenylalanine to tyrosine, whilst patients with alkaptonuria have a defective tyrosine metabolism, producing distinctive urine which darkens when exposed to the air