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However, the specific mechanism involved in this protective effect is unclear

Safety Concerns : There are potential risks associated with high doses, particularly with intravenous administration, which can lead to adverse effects

Random-effects models (restricted maximum likelihood, REML) were fitted to estimate pooled log-HRs, which were then back-transformed for interpretability

Overall, our results demonstrate the significant superiority of a new sublingual form of GSH over the oral form, both in terms of bioavailability and positive effects on oxidative stress

First, the symptoms of RLS tend to get worse at night

Gastrointestinal symptoms (nausea, diarrhea, constipation, abdominal pain) are most common, typically occurring during dose escalation and often improving with continued use