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Some people may experience mild side effects like increased flatulence, loose stools, and weight gain
One of Tesamorelin's most well-established effects is its ability to reduce visceral fat
Pathologic fusion of the Ewing gene EWS to WT1 (t(11;22)(p13;q12)( EWS/WT1 )) has been shown to abrogate the tumour suppressor function of WT1 and to generate an oncogenic chimeric protein capable of binding and activating the IGF-1R promoter (Karnieli et al, 1996)
Both are engineered modifications of the native sequence designed to overcome specific limitations of standard IGF-1 particularly its rapid sequestration by insulin-like growth factor binding proteins (IGFBPs)
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