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Is it effective

For patients without absorption disorders, high-dose oral supplements of 1,000 to 2,000 mcg daily have been shown to be comparably effective at correcting mild to moderate deficiency at lower cost and greater convenience.

Systemic and metabolic conditions such as diabetes, obesity, multiple sclerosis, rheumatoid arthritis, lupus erythematosus, ankylosing spondylitis, as well as Alzheimers disease, Parkinsons disease, chronic depression and autism spectrum disorders also become a growing health problem [1,2,3,4,5,6]

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