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All those pathological conditions result from disturbances in the levels of various brain neurotransmitters such as serotonin (5-hydroxytryptamine (5-HT)) and dopamine

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Unlike normal wound repair, diabetic wounds are frequently arrested in a prolonged inflammatory phase, resulting in delayed epithelialisation and chronic non-healing ulcers

Among the primary human classes of this system, GSTM1 and GSTT1 genes exhibit a deletion polymorphism that leads to a lack of active isoforms when in homozygosis, known as the null genotype [9]

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