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Immunosenescence contributes to: Increased infection risk Slower recovery from illness Reduced vaccine responsiveness Chronic inflammation Greater susceptibility to age-related diseases At the same time , many older adults experience "inflammaging," a state of persistent low-grade inflammation that accelerates biological aging

Furthermore, patient communication and consent processes must evolve to accommodate the flexible and iterative nature of these trials [582, 610]

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[2] [7] What is NAD+

doi: 10.1002/hep.30251 34

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