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Similar results were observed in a study focusing on MC4R deficiency and pharmacotherapy [44] , where MC4R -deficient patients who underwent sleeve gastrectomy achieved stable short-term weight loss (mean 17.99% weight loss within 6 months), but long-term outcomes were heterogeneous and often accompanied by weight regain, requiring revisional surgery in some cases
Saxenda (liraglutide) Saxenda is a GLP-1 agonist with the active ingredient liraglutide
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People Going Blind From GLP-1: Risks, Evidence and Protection Recent reports have raised concerns about potential links between GLP-1 medications and vision problems, prompting questions about whether people are going blind from GLP-1 treatments
Animal models have shown that GLP-1 can increase energy expenditure and regulate heat production and conversion from white adipose tissue to brown adipose tissue in obese mice [42], although human data on this effect are not yet convincing [18,43]
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