0pubmed Fetoni AR, De Bartolo P, Eramo SL, et al
For instance, one study noted that individuals who regularly took vitamin B12 supplements gained between 2.5 to 17 fewer pounds (1.2 to 7.7 kg) over a decade than those who didn't supplement
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Severe or prolonged B12 deficiency can lead to a range of neurological manifestations, including peripheral neuropathy, which may present as pain, paraesthesia (pins and needles), or altered sensation in the extremities
Proliferating white blood cells produce increased amounts of haptocorrin (transcobalamin I) , a B12-binding protein
Initially, both were broadly categorized under metabolic enhancers