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In: Bryan, N., Loscalzo, J

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10.2.3.2 Doses, Associations, and Efficacy Doses have been described in Table 10.4 They can be administered alone as monotherapy or in combination with almost all the other antidiabetic drugs except sulfonylureas and rapid-acting insulin

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For glycemic control, the mean reduction in HbA1c across most T2DM subgroups approaches or reaches the commonly referenced threshold for clinical relevance of 0.5% 47 , and in key target populations (e.g., T2DM with obesity) can reach 0.81.0%, indicating clinically perceptible improvements

If the study enrolled on schedule and data collection is complete, publication could come within the next several months