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In rats, R -lipoic acid was more effective than S -lipoic acid in enhancing insulin-stimulated glucose transport and metabolism in skeletal muscle (110), and R -lipoic acid was more effective than R,S -lipoic acid and S -lipoic acid in preventing cataracts (111)

2.1.4 BBB disruption METH compromises BBB integrity, allowing peripheral immune cells to infiltrate the CNS (Ramirez et al., 2009)

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