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In papers and reviews, DSIP is sometimes linked with the stress axis (the HPA axis)

Photosynthetica 34:321342 Mangano S, Denita-Juarez SP, Choi H-S, Marzol E, Hwang Y, Ranocha P, Velasquez SM, Borassi C, Barberini ML, Aptekmann AA, Muschietti JP, Nadra AD, Dunand C, Cho H-T, Estevez JM (2017) Molecular link between auxin and ROS-mediated polar growth

Prevention or treatment of stress (caused by vaccination, diseases, transport, high humidity, high temperatures or extreme temperature changes)

Castle WB (1962)

On the gastrointestinal front, literature has described mucosal barrier protection via modulation of endogenous prostaglandin (PGE2) and heat shock proteins (HSP70/90)

However, significant questions remain about whether berberine patches actually work