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Here we show that depletion of intracellular GSH does not alter tumour growth and extracellular GSH is highly abundant in the tumour microenvironment, highlighting the potential importance of GSH outside tumours

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Therefore, autophagy is induced to assist the degradation of damaged proteins by lysosome enzymes through autolysosome formation

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Ideally, this framework is further enriched with metagenomic analysis of the gut microbiome, which provides valuable insights for functional decision-making (Proctor et al., 2019), and with a pharmacogenomic profile, particularly in cases requiring pharmacotherapy or where patients are already on complex polypharmacy regimens

Lee KW, Loh HC, Ching SM, Devaraj NK, Hoo FK