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The effect of metformin on islet incretin receptor expression As metformin upregulates the expression of incretin receptors in an islet cell line in vitro [26], we assessed whether metformin modulates pancreatic or islet incretin receptor expression in murine islets

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Its role involves dephosphorylating and activating the Cyclin B/cdk1 complex, which subsequently governs the initiation and advancement of mitosis

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