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The study found that berberine alleviated the severity of symptoms in the multiple sclerosis mouse model, and in primary astrocyte culture, berberine inhibited the increase in sphingosine kinase-1 (SphK1), and Sphingosine-1-phosphate (S1P) induced by lipopolysaccharide

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The plates were incubated for 48 hr at 37C and were stained with 1% crystal violet

It reflects the FDA's ongoing effort to ensure that all compounded medications meet rigorous safety and efficacy standards

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