doi: 10.1080/20002297.2025.2544169 35 LiR.WangJ.XiongW.LuoY.FengH.ZhouH.et al
Hydrogen peroxide is produced naturally in the body during various biochemical processes, but in excess, it can cause oxidative stress, leading to cell and tissue damage
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Once acute liver failure has occurred or seems likely, however, the course of action is intensive supportive therapy or liver transplantation (Ferner 2011)
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As a control, structure of GPX4 R152R was also computationally modeled using the same algorithm, which indeed represents WT GPX4 but excludes artifacts from computational process when compared with the modeled R152H protein structure