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A study in 1996 analyzed the mRNA levels of insulin receptors in the SN of postmortem PD human brains and detected reduced insulin receptor mRNA compared to the control brains [53]
doi: 10.1016/j.clnu.2019.05.004 153 PelliciariSPinatelEVanniniAPeanoCPuccioSDe BellisGet al
Today, the goal is broader: reducing cardiovascular and kidney complications, improving metabolic health, preserving quality of life, and addressing excess body weight when appropriate
proteins were revealed by a chemiluminescent reagent (Clarity, Bio-Rad)
Int J Mol Sci 2020;21