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Hypothermia and other treatment options for neonatal encephalopathy: an executive summary of the Eunice Kennedy Shriver NICHD workshop

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Energy is produced at each stage of the process, and stepwise shortening of acyl-CoA generates one molecule of FADH 2 and NADH for every two-carbon unit released, while each acetyl-CoA molecule yields 3 molecules of NADH, 1 molecule of FADH 2 and 1 of GTP via the tricarboxylic acid cycle

Moreover, ROS can affect the overexpression of p53 and p21 cip1/waf1 , leading to the failure of DNA or apoptosis repair [49]