While no newer medications have officially been approved as adjunctive therapies in type 1 diabetes, there is one source of hope: Inpefa (sotagliflozin)
There are several glucagon-like peptide-1 (GLP-1) medications besides semaglutide, including: Liraglutide ( Saxenda , Victoza) Dulaglutide ( Trulicity ) There are also other medications that treat obesity, type 2 diabetes, and cardiovascular disease
In vitro studies demonstrated that treatment with liraglutide or exendin-4 significantly attenuated oxidative stress and cellular apoptosis in SH-SY5Y cells exposed to methylglyoxal or high glucose, which mimicked the pathophysiological conditions of diabetic neuropathy [79, 80]
doi: 10.1038/sc.2015.183
studies have employed a variety of tools such as the Tinnitus Handicap Inventory (THI), 16 Visual Analog Scale (VAS), 17 and non-validated symptom scores, 18 further complicating data synthesis and meta-analysis
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