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This overview reports BPC-157s definition, proposed biological mechanisms, research status, and regulatory position within sports and military settings, providing concise conclusions followed by supporting context

When methylation demand is high or inefficient, homocysteine may accumulate or be diverted away from glutathione synthesis

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The resulting excitotoxic levels of glutamate disrupt the axonal trafficking of neurofilaments and may contribute to irreversible neurodegeneration (Petrozziello et al., 2022)